As you age, there are those deep wrinkles in the forehead, between the eyebrows, around the eyes, above the lips, called dynamic wrinkles. They're the result of a breakdown of collagen, facial muscles continually creasing the skin by facial expression, exposure to the sun, smoking and natural degeneration. Other folds may get deeper because of the way fat decreases and moves around. Ideally, most of these issues can be managed with the use of Neuromodulators like Botox, Nuiceva, Xeomin and Dysport. For larger wrinkles due to volume loss, fillers compliment neuromodulators. Depending on the thickness of the skin and loss of collagen, other services like Ultherapy or Collagen Builder Treatments can further strengthen and restructure the skin.